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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T12192 | NCGC00229600 | Others , TSH Receptor | |
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies. | |||
T12073 | ML-109 | TSH Receptor | |
ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM) | |||
T5383 | D3-βArr | NCGC00379308 | TSH Receptor |
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation. | |||
T13216 | TSHR antagonist S37 | TSH Receptor | |
TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR). | |||
T29087 | VA-K-14 hydrochloride | VAK14 Hydrochloride,VA K 14 HCl,VA-K-14 HCl,VAK14 HCl | TSH Receptor |
VA-K-14 hydrochloride(VAK14 HCl) is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogate... | |||
T13072 | Taltirelin acetate | TA-0910 acetate | Thyroid hormone receptor(THR) |
Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)). | |||
T13217 | TSHR antagonist S37a | Others | |
TSHR antagonist S37a is a selective antagonist of thyrotropin receptor (TSHR), with potential for the treatment of Graves' orbitopathy. | |||
T38226 | TSHR antagonist S37b | ||
TSHR antagonist S37b, the less potent enantiomer of TSHR antagonist S37a, exhibits minimal efficacy in inhibiting the thyrotropin receptor (TSHR). It is utilized in thyroid function research[1]. | |||
TP2011 | JKC363 | JKC 363 | |
Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 0.5 and 44.9 nM at MC4 and MC3 respectively) that antagonizes the effects of α-MSH. Suppresses thyrotropin-releasing hormone (TRH) release, atten... | |||
T7590 | Taltirelin | TA-0910 | Thyroid hormone receptor(THR) |
Taltirelin (TA-0910) is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release))[1]. | |||
TMIH-0550 | Taltirelin-13C-d3 | ||
Taltirelin-13C-d3 is the 13C and deuterated compound of Taltirelin. Taltirelin has a CAS number of 103300-74-9. Taltirelin is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 ... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T6956 | Protirelin | Lopremone,pGlu-His-Pro-NH2,Synthetic thyrotropin-releasing hormone,Thyroliberin,TRH,TRF | Thyroid hormone receptor(THR) , Endogenous Metabolite |
Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin. |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-06821 | THRB Protein, Human, Recombinant (His) | Human | E. coli |
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin... |